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Adipose Processing

Celling Technologies is researching alternative sources for adult stem cells. Current data indicates that adipose tissue is a rich source of mesenchymal stem cells. Celling Technologies recognizes this opportunity and has collaborated with industry-leading engineers and scientists to develop innovative cell therapy systems specially designed to process adipose tissue.

Tissue Genesis:

The Tissue Genesis Cell Isolation System is designed to make adipose-derived regenerative medicine a convenient reality for both doctors and patients. The Cell Isolation System is an operating room (OR)- ready, CE-marked, good manufacturing practices (GMP)-certified system. A fully automated platform technology, the Tissue Genesis Cell Isolation System consistently separates and extracts tens of millions of cells from a patient’s liposuctioned adipose tissue in about an hour, with minimal operator manipulation. The proprietary process ensures that the isolated nucleated cells maintain viability and functionality, for immediate use by the patient’s physician. The compact desktop unit readily fits into any standard OR environment and uses preconfigured disposables for quick and easy preparation.

How it Works:

In Tissue Genesis’ proprietary procedure, a small amount of adipose tissue is liposuctioned and processed into a pellet of regenerative cells that include microvascular endothelial cells, adult stem cells, and other cells. These cells can then be delivered back to the patient in a variety of means to accommodate specific procedures, such as being coated onto a vascular graft or stent, or directly injected into damaged tissue, such as ischemic heart tissue following a heart attack.

The system is designed to provide speed, performance, and dependable results in a fully-automated system. Just follow these simple steps:

1. Use the harvesting kit to collect adipose tissue
2. Set-up the instrument with disposables using easy-to-follow
on-screen instructions
3. Load extracted tissue
4. Press “GO” and walk away!
5. One hour later, retrieve syringe of ready-to-use cells
6. Administer cells to the patient

Current and potential near-term applications for the Tissue Genesis Cell Isolation System include:

• Coating of implantable devices such as vascular grafts and stents
• Repair of tissue damaged by heart disease and peripheral vasular disease
• Orthopedic applications
• Aesthetic and reconstructive applications
• Acute and chronic wound repair
• Veterinary applications

THE TISSUE GENESIS CELL ISOLATION SYSTEM HAS NOT BEEN EVALUATED BY THE US FDA FOR HUMAN USE. LIMITED BY U.S. LAW TO INVESTIGATIONAL USE.